IMPROVEMENTS ON ZINC-OXIDE - EUGENOL DENTAL CEMENT BY POLYMERIZATION AND MODIFICATION OF EUGENOL AND ISOEUGENOL.

Description

Main Author

STANNARD, JAN GREGORY

Language(s)

English

Published

1981.

Subjects

HEALTH SCIENCES, DENTISTRY

Summary

Cell culture toxicity measurements were conducted at 18 hour exposures. Cements containing H(,2)PtCl(,6) were equal in "toxicity" to ZOE cements. A toxic response was elicited by H(,2)PtCl(,6). Eugenol alone was "toxic" at 0.081 mM. Isoeugenol was equal in "toxicity" to eugenol from 0.081- 1.399 mM. Isoeugenol cements were equal in "toxicity" to ZOE cements.
pre-mixing.
A "multifunctional" chelation approach to ZOE setting was also evaluated. When 2,5-dimethoxyhydroquinone, I, was mixed at its melting point with zinc oxide, a CS of 48.3 MN/m('2) was obtained which was compared to 36.5 MN/m('2) for an unmodified cement. Pre-mixing I or 5,5'-methylene disalicylic acid, II, with zinc oxide at their melting points before mixing with eugenol increased the CS to I-24.1 and II-26.8 compared to 9.3 MN/m('2). Formation of a zinc eugenolate-like structure resulted from this
Isoeugenol when mixed with zinc oxide showed a CS of 30.6 MN/m('2) compared to 9.3 MN/m('2) for a comparable ZOE cement. Polymerization of isoeugenol with H(,2)PtCl(,6) and acetic acid, with zinc oxide increased the CS to 57.38 MN/m('2). The control cement was rubber-like at two weeks.
In vitro polymerization of eugenol using a thermal procedure produced a polymer resembling an addition polymer. Elemental analysis indicated some oxidation polymerization had occurred, but considerably less than lignin-like polymers. Solution of this polymer in eugenol, 4%, improved the CS to 9.3 (13.68) MN/m('2) for an experimental cement. Polymer addition, however, was not optimized.
values obtained by polymerization in parentheses: CS 46.1 (69.0) MN/m('2); TS 4.241 (5.24) MN/m('2); E 2600 (4000) MN/m('2); W 22.3 (15.4) 10('-4) mm('3)/mm. Addition of H(,2)PtCl(,6) and acetic acid in combination improved these values over acetic acid alone. The use of H(,2)PtCl(,6) alone produces similar values, however, the setting time was greatly retarded.
The purpose was to evaluate polymerization as an approach to strengthening zinc oxide-eugenol (ZOE) cements. The polymerization of eugenol provided statistically significant increases in compressive strength (CS), tensile strength (TS), modulus of elasticity (E) and wear resistance compared to the normal chelate setting reaction alone. To produce this reaction chloroplatinic acid, H(,2)PtCl(,6), and acetic acid were added to eugenol and mixed with zinc oxide. Control values are reported followed by

Physical Description

195 p.

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