Studies on the mechanism of action of ionizing radiations.
[Part] VI,
The oxidation of thiols by ionizing radiations /
by E.S. Guzman Barron [and] Veronica Flood.

Description

Main Author

Barron, Eleazar S. Guzman, 1898-

Related Names

Flood, Veronica.
University of Chicago.
Argonne National Laboratory.
U.S. Atomic Energy Commission.

Language(s)

English

Published

Oak Ridge, Tenn. : U.S. Atomic Energy Commission, Technical Information Division, 1949.

Subjects

Thiols.
Ionizing radiation.

Summary

Thiol compounds, such as glutathione, 2,3-dimercaptopropanol (BAL), propane-1,3-dithiol, and N-phenylaminopropanedithiol, were readily oxidized by x-rays, beta rays, and gamma rays. The ionic yield for this oxidation was about the same, 3 at pH 7, on irradiation with x-rays and with beta rays; it was 23 per cent less on irradiation with gamma rays. The ionic yield varied with the hydrogen ion concentration, increasing as the pH value increased. There was no reduction of oxidized glutathione on irradiation with dosages of x-rays and gamma rays which produced oxidation of the reduced compound. In the absence of oxygen, the oxidation of thiols by ionizing radiations was only 33 per cent of that obtained in the presence of dissolved oxygen. When the thiol solutions were irradiated in the presence of dissolved oxygen, catalase protected them from oxidation by 17 to 27 per cent.

Note

Work performed at the Argonne National Laboratory, University of Chicago.
"AECU-530; (UAC-103)."

Physical Description

17 p. : ill. ; 27 cm.

Locate a Print Version

Find in a library

Viewability